Nutrition articles

NutraIngredients-USA’s 10 Most Read Articles of 2021

1. CRN: “This is not the last word on NAC”​

Published in May as Amazon moved forward to remove NAC-containing dietary supplements from its website, this article, which attracted more than 80,000 page views, covered CRN’s response to the current situation. Fast forward seven months and there has still been no resolution to the issue, with the FDA continuing to state that it has not yet made a final decision.

2. FDA Seizes $1.3 Million Worth $1.3 Million in “Adulterated Dietary Supplements” Containing Kratom

Another story from May, this time around the seizure of more than 207,000 units of dietary supplements and bulk dietary ingredients containing kratom worth approximately $1.3 million by U.S. Marshals, acting at the request of the US Food and Drug Administration.

“There are significant concerns about the safety of kratom, the risk it may pose to public health and its potential for abuse,”said Judy McMeekin, Pharm.D., associate commissioner for regulatory affairs at the FDA, at the time of the raid.

3. House Resolution aims to recognize the benefits of vitamin D for COVID-19

There has been much interest in associations between vitamin D status and COVID-19 outcomes, and this article covered the introduction of a resolution in the United States House of Representatives to recognize the benefits .

Rep. Glenn Grothman (R-WI) introduced the resolution in February to “to unite the voice of the House of Representatives in finding additional ways to limit the negative effects of COVID-19 and hopefully encourage our public health establishment to release much-needed advice on the true effectiveness of vitamin D in the prevention of serious symptoms, complications or death from the coronavirus.

4. Vitamin D supplements linked to increased microbiome diversity

Our report on a study published in Scientific Reports on the potential of vitamin D to beneficially alter the composition and diversity of the gut microbiota in vitamin D deficient/insufficient but otherwise healthy women was the fourth most read article of 2021.

Independently commenting on the study results, Glenn Gibson, Professor of Food Microbiology and Head of Food Microbial Sciences at the University of Reading in the UK, told NutraIngredients-USA: “This is a very well done study that shows interesting in vivo results. The positive effects of vitamin D on the microbiome are notable.

“Additionally, the trial may be relevant to the current COVID pandemic given that both appear to have an implication in aiding entomology.”

5. Judge decides to invalidate two NR patents in Elysium Health victory

Lawsuits and countersuits between New York-based Elysium Health and California-based ChromaDex began in 2016, and a few judgments have been issued in quick succession during the second half of 2021. The top five close of our most widely read stories was our coverage of U.S. Judge Colm Connolly’s decision of the United States District Court for the District of Delaware to grant Elysium Health’s request to invalidate two Dartmouth College patents under license from ChromaDex regarding nicotinamide riboside.

Elysium had been charged with infringing both patents – U.S. Patent No. 8,383,086 and U.S. Patent No. 8,197,807. However, Judge Connolly granted Elysium’s motion for summary judgment, stating that the patents in question were invalid because nicotinamide riboside, a form of vitamin B3, is a naturally occurring vitamin and therefore ineligible for patent (Alice Corp. Pty. v. CLS Bank Int’l, 573 US 208, 216 (2014)).

6. Study: Curcumin extract fights the double whammy of gut discomfort and anxiety

Curcumin and turmeric remain ‘hot’ herbs, and a study published in early 2021 found that a daily dose of 500mg of the DolCas brand Curcugen ingredient was associated with greater improvement in digestive and anxiety levels in adults with self-reported digestive disorders.

Data from the eight-week study was published in BMC Medicine and Complementary Therapies.

7. Patients with more omega-3s in their blood are less likely to die from COVID-19, pilot study finds

This pilot study focused on analyzing blood samples from 100 patients being treated for COVID-19 at Cedars Sinai Medical Center in Los Angeles. The samples were analyzed using the OmegaQuant test for the Omega-3 Index, with results showing that people with the highest levels of EPA and DHA in their blood were 75% less likely to die than those of the lower three quartiles.

The data has been published on the medRχiv portal and has not been peer reviewed.

Lead author Arash Asher, MD, director of cancer survivorship and rehabilitation at Cedars-Sinai, said the results are highly suggestive and promising.

“Although not meeting standard statistical significance thresholds, this pilot study – along with multiple lines of evidence regarding the anti-inflammatory effects of EPA and DHA – strongly suggests that these marine fatty acids available on the nutritional plan may help reduce the risk of adverse effects in COVID-19 patients. Larger studies are clearly needed to confirm these preliminary results.”he said.

8. Study: Vitamin D Levels Associated with Depressive Symptoms​

Vitamin D made another appearance on our most-read list, this time with a study from the summer indicating that higher levels of the sunshine vitamin may be associated with fewer symptoms of depression.

“To our knowledge, this is the first work examining the role of inflammation in the relationship between depressive symptomatology and serum vitamin D levels using mediation and moderation analyzes in a community sample. We found negative correlations between vitamin D levels and depressive symptomatology (assessed by the CES-D score) and three inflammatory markers (CRP, IL-6, WBC), which were in turn positively associated with depressive symptomatology », write the researchers.

9. Review finds magnesium relieves symptoms of diabetes

More science in the top 10, with results from a systemic review and a meta-analysis of data from 25 randomized, placebo-controlled trials indicated that oral magnesium supplementation can improve glucose parameters in people with diabetes.

write in Nutrients​, Italian, Sudanese and British scientists have also reported that magnesium supplementation may also improve markers of glucose and insulin sensitivity in subjects at high risk of diabetes.

10. ABC article sheds light on purslane’s long history of use as Chinese researchers uncover other plan components

To close out the top 10, we covered an article published in HerbalGram on purslane, a succulent ground cover plant with fleshy, oval leaves.

The medicinal potential of the plant has been a topic of interest since ancient times, with modern research focusing on purslane’s benefits for asthma and diabetes. Other studies have focused on its neuroprotective effects. It may even have antitumor activity and antimicrobial properties.

Thank you!

The NutraIngredients-USA team wishes you a very happy holiday season.